i was trying to put tom scott underwaterr to make it look like he was drowning but i think i just accidentally created something beautiful here. he is in awe of beauty of the self and nature
This image hurts my brain more than the original debate ever did. Brains are dumb.
i wanted to like make sure this was legit and stuff so i took a section of the left and stretched it over to the right and jesus fuck
rb for the last pic being the best demonstration by far
“This is why I draw in black and white” was all my sleepy, horrified boyfriend could say.
Holy…. you know what… this last image is probably the only image that has ever been able to convince me this brain hack was a real thing and we didn’t all just roar onto the battlefield because half of us had been hideously duped… we were all duped. By our own brains.
does tumblr know about tim misny??? like has the level of tim misny awareness that exists in northeast ohio broken containment and become known online yet???
ok so tim misny is a personal injury lawyer here in ohio.
that’s him. you do not have to remember his face from this image because you’re gonna see it a lot in this post. so mainly i think we all kinda honed in on tim misny because of his slogan
he’s gonna make them pay. he’s gonna get you that money but also it’s a little threatening like he’s gonna fully fuck his legal opponent’s shit up. this sprung tons of local memes. then there were the billboards which were normal at first.
but here’s the thing; we already know what misny does. he makes them pay. so it turns into just saying “you know what i do” which is funny enough if you don’t at all have the context.
but this is not where the absurdity caps out, my friends. no. this is what it has evolved to and they. are. everywhere.
that’s right. no text. just the judging eyes of tim misny, glaring through our skin and into our souls. there is no god. there is no devil. there is just tim misny and he’s gonna make them pay.
In fun new “tumblr’s tag search is a literal fucking nightmare” discoveries, apparently using the word “Malik’s” twice in one post is enough to make it disappear. The name itself is fine, but in the possessive it’s apparently illegal to use more than once
(For those following along at home, that means the other post that had issues a couple months ago? the issue might not have been the word “weapon”, it could’ve been just using one of the leads’ name in the possessive more than once what the *fuck* tumblr)
This is better than I’d ever hoped for, I bet a rat could kill you with that thing by firing a laser back in time and electrocuting your grandfather
Just look at this thing
The rat gun is hereeeeee!
This is getting notes again so I will admit that “rat gun” was an autocorrect error and it was supposed to be “ray gun.”
But it’ll always be a rat gun to me.
The most expensive thing in these pictures was the cat, and he was $60.
I’ll be honest–I forgot that the pump organ desk/bar was visible in the background, and it was NOT under $60.
It was actually $75.
The chairs, however, were paid for in human life. I inherited them; they were originally my great grandmother’s. But they’re not particularly rare– you can find these exact chairs without a lot of effort, in reasonable shape, for not that much money. They made a lot of them.
your gazelle has a pearl choker
That’s Hadrian. He’s a bush buck and he loves fashion.
Hi you asked this question and I immediately went to the pottery studio to make a calcifer to put in my woodstove.
Will update if he survives the kiln.
i am still on tenterhooks vis a vis calcifer 🥺🥺🥺
I just brought him home from the pottery studio and wired him for light. He lives!!!!!
OP just wondering do you like have the closet to Narnia tucked in there somewhere?
Dude, c'mon, these things take time.
Give me a couple hours.
Okay!! We have doordrobe! It’s not quite done but after nearly turning myself into an hellpancake while carrying this in from the garage to the house, I feel like I should call it a night.
Right now it’s not going into a secret room (but the Angel of Death (And WiFi) behind it does have a secret compartment for my router? Does that count) but Malice and Vice are still exploring it like it’s a whole new world.
The House of Horrors continues to be…well, exactly what it is.
Oh, no, all radioactive materials go in The Box.
please explain. Do you actually have a lead lined box for radioactive objects, or are you just talking about the router behind the painting?
The Box.
Doxxing this person:
whoah hey man don’t give out my address to strangers on the internet they’re gonna mess with my schemes.
and anyways I’m not sure yet if I want to install a lightning effect ceiling. It’s cool but it would be hard to dust…
BP did hire PR firm Ogilvy & Mather in 2004, and coined the term ‘carbon footprint’ as well as creating the 'carbon footprint calculator’. This gave the impression that climate change was primarily the fault of the individual consumers.
From a New York Times opinion piece on carbon footprint (via the Wayback Machine): 'In 2004, BP hired the public relations firm Ogilvy & Mather to improve its image, in part by conveying the message that consumers of oil and natural gas bear the responsibility for their greenhouse gas emissions, not the producers of the oil and gas they use. The result was BP’s ingenious carbon footprint calculator, which allows individuals to calculate the carbon emissions that result from their activities.’
From a BBC Future article on 'how companies blame you for climate change’: 'Similar criticisms have been levelled at terms like “carbon footprints” – which was first coined in a 2005 TV advert from BP. The advert appears to show members of the public being stopped in the street and asked what is “their carbon footprint”.’
From an Irish Times on individualising blame: 'In 2004, it unveiled a “carbon footprint calculator”, so that individuals could assess how much their daily activities were polluting the planet. The marketing campaign, led by Ogilvy & Mather, fostered the false idea that climate change was the fault of individuals rather than fossil fuel companies.’
So much translation discourse just boils down to monolinguals not understanding that “coolness” doesn’t translate across languages, and you need to re-add it manually on the other end.
Spanish and French understand the anglicism so just say “eso es muy cool” or “c'est très cool” if the context is not particularly formal
No no, not literally the word “cool” I mean the [concept of coolness]. Things that sound cool, poetic, funny, dramatic, etc in one language will completely fail to land if you simply go 1-to-1 word equivalents.
In the Japanese version of Fullmetal Alchemist, the antagonists are named after the seven deadly sins, in English. As in, rather than the Japanese word, “Greed” is still Greed in the original.
Because loan words from English are often pretty “cool”, as with your Spanish and French example.
But this presents a problem, because, to give them a bit of flair, the antagonists are sometimes given a proper Japanese adjective along with their name, to make a sort of title of sorts.
“GreedyGreed”
The italicized part would be a Japanese adjective, and the bolded part is an English loanword. This is fine in Japanese, but would be totally nonsense in an English translation.
After all, it’s common sense to keep the names the same, duh, and obviously the whole point of what you’re doing is to translate the Japanese.
Greedy Greed. You cannot call him that.
You can’t go 1-to-1. To keep the [concept of coolness], you have to identify what made the original cool, and then recreate it in the new language.
And here, we have a foreign word, and a native word, both meaning the same thing, paired together to give an antagonist a cool sounding title. So how do we do that in English.
Well, the seven deadly sins, being Christian and Catholic and all, have fancy names in Latin. Or well, they just sound fancy in English, because Latin was the language of intellectuals for a long long time.
And in fact, while we also have the word “greed”, English has a fancier sounding word that means the same thing, but whose etymology comes from the fancy Latin. That might give a similar cool-loanword feeling, right?
One of my favorite things about biology is that there are so many diagrams like this that look like shitposts if you remove any and all context from them
The stage that they’re at is animal testing but it sounds like it’s been successful in mouse and primate models.
My understanding: The way autoimmune diseases usually seem to work* is the immune system is “flagging” the wrong thing as harmful/not needed and destroying it. The typical treatments for autoimmune diseases are just tamping the entire immune system down so it can’t destroy anything, which leaves a person vulnerable to infection.
The newer method is basically “tricking” the body using a method that… the human body already came up with. Cells flagging the wrong thing apparently happens all the time, so there are multiple defenses against immune disease, and one of them is in the liver. So scientists figured out a way to tell the body “hey, you flagged this wrong” and sent it to the liver and the liver/body recognized this signal.
There is still a lot of work to be done and it sounds like this isn’t foolproof (ie: what if the liver is whats broken? unsure, and what if the immune system flags things wrong again?) but this is literally so amazing. i was tearing up reading it, and i hope that everything goes well in clinical trials.
*theres like a lot medical science doesnt know about the immune system
Thank you for this explanation/synthesis of the article! It’s important for us to understand that they’re still in early development and testing of these methods, but also that they’ve seen it work in mice and primates (rather than just petri dishes of human cells). I hope this goes well.
Hi! I’m a microbiologist and I’ve done work in academia, pharma, and clinical trials.
So the most exciting thing about this article is the last paragraph tbh (working on getting the actual paper, it’s not up on sci-hub yet).
The company mentioned, Anokion, has four registered clinical trials for both Celiac and MS patients. The trial for Celiac just submitted data from their phase 1 trial (meaning there’s good data it is safe) and are recruiting for a Phase ½ trial (meaning they are now testing efficacy). After that, the big hurdle is phase 3, which looks at whether or not it is better than a current treatment. The projected completion date is spring 2025. They are also preparing for a Phase 2 trial but are not yet recruiting.
The phase 1 MS trial is currently active, estimated completion in summer 2024.
I checked the company website and it looks like they are in the process of submitting an investigational new drug (IND) application for Type 1 diabetes. This is the first step to starting clinical safety and efficacy trials.
Now clinical trials can get delayed for a variety of reasons, but this is a really good sign! It’s way further along than I initially thought when seeing the news. If the treatment does well, we could see new drugs on the market for Celiacs as early at 2030ish and MS as early as 2035.
I literally just burst into tears and woke up my partners.
Holy shit. The idea of not having celiac disease anymore is so completely overwhelming.
Update: I have registered for the trial and if you also have celiac and want to register the link is here.
wait would this also be able to reverse allergies like peanut allergies?
Allergies can work differently than autoimmune disorders, so a safe bet would be probably not. But that doesn’t mean this research won’t serve as a launch point for allergy elimination in the future.
Plus there are remedies for allergies already, but I’m not sure if peanut is covered.
Lmao one of Google’s witnesses fucked up and leaked the exact percentage of Google’s revenue that it shares with Apple in exchange for default search enginge status, a number that has remained redacted up until now
I cannot stress enough that he DID NOT HAVE TO tell the world the Google shares
36
Goddamn
Percent
of its revenue with Apple in order to maintain default search engine status
Since we know that Google paid Apple $26.3 billion in 2021 to be the default search engine on Apple products, that means Google made 73 BILLION DOLL-HAIRS from its default placement agreement with Apple ALONE, which is more than 1/3 of its total search engine ad revenue, which as you can imagine is a huge part of its overall revenue
The same guy also tried to argue that monopolies are somehow good for competition. He didn’t even deny that Google has one. Said they should be allowed to expand it, even. You can’t make this shit up lmao
*slaps Adam Smith’s Wealth of nations on the table* MONOPOLIES! ARE! BAD! Heck, it means if you know that part alone, you are more qualified than that guy to lead Google!
there are FERNS?? that grow like TREES???? no fucking way
so what sent me down this rabbit hole is earlier on a walk with my husband we saw some glorious “palms” in a garden that were about 6 feet high, once i inspected the fern-like leaf pattern and saw the new leaves were curled i was blown away because it was so similar to a fern but had a trunk and i didnt know ferns could grow like that. (see the last two images, i took them so i could identify it later using an app + research, it might be sphaeropteris brunoniana) look how hairy that frond is! i love plants 🤎ferns my beloved🤎
With Netanyahu’s initial reaction to the video of the three women hostages, calling it propaganda etc, it’s good to remember that saving hostages is not even the least of israel’s priorities right now, and as it was summed up perfectly:
Rescued hostages who may contradict the narrative are a potential embarrassment.
Dead hostages are capital they can spend to further justify genocide.
Like they literally would rather not! And you have to think about this the next time you hear zionists advertise israel as the “safe haven” for Jewish people around the world
